The Minicare HNL wins the Horizon Prize – a device which could help reduce the misuse of antibiotics

A handheld device, which can differentiate between bacterial and viral infections, and could help reduce the number of incorrectly prescribed antibiotics, has won the first ever European Union ‘Horizon Prize – Better Use of Antibiotics’ in Leuven, Belgium. The HNL test, developed by Royal Philips and Diagnostic Development, uses the Philips’ Minicare I-20 handheld diagnostic … Read more…

Gene discovered which can prevent the emergence of drug-resistant TB

New research has highlighted a gene, NucS, which can prevent tuberculosis-causing bacteria from mutating into antibiotic resistant strains. The work was carried out by scientists from the University of Sussex, UK, and the Centro Nacional de Biotechnologia, Madrid, and was published on the 27th January 2017 in Nature Communications. NucS is a gene which is … Read more…

ClyF – a novel chimeolysin with a grudge against MRSA

Scientists have discovered a novel lysin which could be a valuable new tool in the fight against MRSA. The paper, which was published on January 9th in Nature, highlighted a novel chimeric lysin, called ClyF, which showed promising activity against MRSA both in vitro and in murine infection models, in vivo. From a library of … Read more…

Carbon dots – a novel antibacterial that could stop MRSA in its tracks

New research has shown that a nanomaterial composed of carbon ‘dots’ could be effectively used in the fight against MRSA. The work, which was carried out by scientists at Shiraz University of Medical Sciences and Islamic Azad University, revealed that carbon dots, or c-dots, are capable of killing both wild-type Staphylococcus aureus and their methicillin-resistant … Read more…

A major antimicrobial additive could cause antibiotic tolerance in bacteria

A recent study has given evidence to suggest that a popular antimicrobial additive plays a part in inducing bacterial tolerance to some of our most powerful antibiotics. The research, which was carried out by microbiologists at Washington University, Corey Westfall and Petra Levin and is still in the peer-review stage of publication, showed that bacteria … Read more…

Treating biofilms to an antimicrobial ‘cloak’

Researchers have developed an antimicrobial ‘cloak’ which could play a key role in helping to protect us from the build-up of dangerous microbial biofilms. In their paper published on the 5th of December in Scientific Reports the team found that an agar hydrogel, containing graphene-oxide and laser printed to mimic the shell surface of the … Read more…

A living antibiotic?

We may have found a new ally in the fight against antibiotic resistance… though it might not be what you’d expect. Researchers have found exciting evidence to suggest that a predatory bacteria, Bdellovibro bacteriovirus, could be used to deal with dangerous bacterial infections as a ‘living antibiotic’. The study, published on the 23rd November in … Read more…

Dangerous genes above Beijing

Polluted air could be a major way for resistance-allowing genes to be spread across bacteria, as researchers have determined using air samples taken from smog in Beijing. Joakim Larsson, director of the University of Gothenburg’s Centre for Antibiotic Resistance Research, and his team analysed 864 DNA samples from a range of human, animal and environmental … Read more…

Old enemies, new hope – β-lactams could be used alongside other antibiotics to kill MRSA

Old enemies, new hope – β-lactams could be used alongside other antibiotics to kill MRSA

Oxacillin, a β-lactam antibiotic, can reduce the virulence of MRSA and open it up to attack from the host immune system and other antibiotics, new research has shown. MRSA (Methicillin Resistant Staphylococcus aureus) is one of the most dangerous pathogens affecting the world at the moment, with 20% of infected patients dying from systemic infections … Read more…