A novel antibiotic treatment inspired by our immune system

Researchers from the National University of Ireland Galway have developed a new antibacterial treatment, effective against drug-resistant bacteria, which takes inspiration from the human immune system. This treatment, called the ‘iodo-thiocyanate complex’, or ITC for short, also showed a low propensity to lead to the development of resistant bacterial strains. The paper was published on … Read more

New test could rapidly identify colistin-resistant bacteria

Researchers have found a method to identify bacteria showing one of the most dangerous forms of antibiotic resistance, in a test that’s both quick and cheap to run. Dr Laurent Dortet, an Associate Professor at South Paris University and his colleagues at Imperial College London, Dr Gerald Larrouy-Maumus and Professor Alain Filloux, presented their work … Read more

Researchers uncover the structure of anti-TB drug target, and identify a new weapon against the deadly disease

The fight against TB has taken several promising steps forward – scientists from Rutgers University have not only uncovered vital new information about how rifampicin, the frontline anti-TB drug, binds to its target, but have also discovered a completely new class of compounds that specifically kill TB bacteria. The paper was published in the journal … Read more

Not just a tasty snack – maple syrup can boost the power of antibiotics

Enjoy maple syrup with your pancakes? An ongoing study suggests that the popular kitchen companion contains extracts which could boost the power of antibiotics, significantly reducing the amount of drug needed to kill infectious bacteria. On the 2nd April, Dr. Nathalie Tufenkji presented the latest information on the study at the ‘253rd National Meeting & Exposition … Read more

Saving your eyesight: New research suggests chlorin e6 could protect against bacterial keratitis

A structure known as chlorin e6 (Ce6) could be used in photodynamic inactivation (PDI) therapy to protect patient’s eyes from the dangerous effects of Pseudomonas aeruginosa keratitis, new research has shown. The paper, which was published on 15th March 2017 in Nature Scientific Reports, showed that when the eyes of mice were infected with multi-drug … Read more

Pentamidine, wingman for the antibiotics: A new two-step approach to fight infections

A new dual therapy approach to fight multi-drug resistant gram-negative bacteria has been uncovered – and, interestingly, it involves an existing antifungal and antiprotozoal drug. Dr. Eric Brown, professor of biochemistry at McMaster University, and his team showed that pentamidine, a drug normally used to treat protozoan and fungal infections, is effective against drug-resistant gram-negative bacteria when … Read more

Nursing homes rarely use isolation precautions against multi-drug resistant infections, a recent study shows

Nursing homes may be infrequently applying isolation precautions to prevent the spread of infections caused by multi-drug resistant organisms (MDRO), a recent study suggests. The study, which was published on the 17th February 2017 in The Journal of the American Geriatrics Society, was carried out at Columbia University School of Nursing in an attempt to … Read more

WHO produces a list of the 12 most dangerous bacteria

The World Health Organisation (WHO) has published a list of the 12 bacterial families against which new antibiotics are desperately needed. Unveiling the list on the 27th February 2017, WHO hopes that this list will spur the research and development of new antibiotics at a time when the drugs we’ve come to rely on to … Read more

Gene discovered which can prevent the emergence of drug-resistant TB

New research has highlighted a gene, NucS, which can prevent tuberculosis-causing bacteria from mutating into antibiotic resistant strains. The work was carried out by scientists from the University of Sussex, UK, and the Centro Nacional de Biotechnologia, Madrid, and was published on the 27th January 2017 in Nature Communications. NucS is a gene which is … Read more

ClyF – a novel chimeolysin with a grudge against MRSA

Scientists have discovered a novel lysin which could be a valuable new tool in the fight against MRSA. The paper, which was published on January 9th in Nature, highlighted a novel chimeric lysin, called ClyF, which showed promising activity against MRSA both in vitro and in murine infection models, in vivo. From a library of … Read more