Pentamidine, wingman for the antibiotics: A new two-step approach to fight infections

A new dual therapy approach to fight multi-drug resistant gram-negative bacteria has been uncovered – and, interestingly, it involves an existing antifungal and antiprotozoal drug. Dr. Eric Brown, professor of biochemistry at McMaster University, and his team showed that pentamidine, a drug normally used to treat protozoan and fungal infections, is effective against drug-resistant gram-negative bacteria when … Read more

WHO produces a list of the 12 most dangerous bacteria

The World Health Organisation (WHO) has published a list of the 12 bacterial families against which new antibiotics are desperately needed. Unveiling the list on the 27th February 2017, WHO hopes that this list will spur the research and development of new antibiotics at a time when the drugs we’ve come to rely on to … Read more

A major antimicrobial additive could cause antibiotic tolerance in bacteria

A recent study has given evidence to suggest that a popular antimicrobial additive plays a part in inducing bacterial tolerance to some of our most powerful antibiotics. The research, which was carried out by microbiologists at Washington University, Corey Westfall and Petra Levin and is still in the peer-review stage of publication, showed that bacteria … Read more

Treating biofilms to an antimicrobial ‘cloak’

Researchers have developed an antimicrobial ‘cloak’ which could play a key role in helping to protect us from the build-up of dangerous microbial biofilms. In their paper published on the 5th of December in Scientific Reports the team found that an agar hydrogel, containing graphene-oxide and laser printed to mimic the shell surface of the … Read more

A living antibiotic?

We may have found a new ally in the fight against antibiotic resistance… though it might not be what you’d expect. Researchers have found exciting evidence to suggest that a predatory bacteria, Bdellovibro bacteriovirus, could be used to deal with dangerous bacterial infections as a ‘living antibiotic’. The study, published on the 23rd November in … Read more